The Rab27 family of small GTPases plays a pivotal role in regulating the exocytosis of various vesicle types, particularly multivesicular endosomes (MVEs), which are precursors to exosomes. These nanometer-sized extracellular…
**Background** Sleep regulation and the physiological response to stress are critical components of maintaining systemic homeostasis. Neuropeptides play a pivotal role in modulating these processes, often acting as signaling molecules…
Synthetic polyampholytes have attracted significant attention due to their ability to undergo reversible conformational changes in response to environmental stimuli, mimicking the dynamic behavior of biological macromolecules. This study presents…
**Background** Tubulin is a critical protein that polymerizes into microtubules, which are essential for various cellular processes, including cell division, intracellular transport, and maintaining cell structure. Dysregulation of microtubule dynamics…
This study investigated the impact of combining fish protein with fish oil on lipid metabolism in male Wistar rats. Four experimental groups were established: a control group fed casein (20%)…
**Background** Src family kinases (SFKs) are a group of non-receptor tyrosine kinases that play critical roles in regulating cell growth, adhesion, migration, and survival. Dysregulation or overexpression of SFKs is…
The melanoma differentiation-associated gene-7 (MDA-7), also known as interleukin-24 (IL-24), was originally identified from human melanoma cells induced to undergo terminal differentiation through treatment with interferon and mezerein. This cytokine…
**Background** Vitamin K plays a critical role in various physiological processes, most notably in the activation of coagulation factors for blood clotting and the regulation of bone metabolism. Osteoporosis, characterized…
A study was conducted to examine the relationships among neuroprotective factors and cytokines in brain tissue from mice at different ages, specifically assessing the impact of dietary restriction on protection…
**Background** Myosin II is a motor protein essential for muscle contraction and cellular motility, playing a critical role in the physiological function of cardiac and skeletal muscles. Dysregulation of myosin…