Product Name :
Rabbit anti-CREB3L1 Polyclonal Antibody(C-term)
Synonym :
Cyclic AMP-responsive element-binding protein 3-like protein 1; cAMP-responsive element-binding protein 3-like protein 1; Old astrocyte specifically-induced substance; OASIS; Processed cyclic AMP-responsive element-binding protein 3-like protein 1; CREB3L1
Host :
Rabbit
Species Reactivity:
Human, Mouse
Specificity :
This CREB3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 481-509 amino acids from the C-terminal region of human CREB3L1.
Predicted Reactivity:
Applications :
WB~~1:1000IHC-P~~1:50~100FC~~1:10~50
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long time storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Signal Transduction
Background :
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity).
UniProt :
Q96BA8
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Purified Rabbit Polyclonal Antibody (Pab) |Synonym Cyclic AMP-responsive element-binding protein 3-like protein 1; cAMP-responsive element-binding protein 3-like protein 1; Old astrocyte specifically-induced substance; OASIS; Processed cyclic AMP-responsive element-binding protein 3-like protein 1; CREB3L1 |Host Rabbit |Specificity This CREB3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 481-509 amino acids from the C-terminal region of human CREB3L1. |Species Reactivity Human, Mouse |Applications WB~~1:1000IHC-P~~1:50~100FC~~1:10~50 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long time storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |Research areas Signal Transduction |Target |Background Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity). |Cellular localization Endoplasmic reticulum membrane; Single-pass type II membrane protein |UniProt Q96BA8 |References |References Guillou,L., Am. J. Surg. Pathol. 31 (9), 1387-1402 (2007)Omori,Y., Biochem. Biophys. Res. Commun. 293 (1), 470-477 (2002) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-CREB3L1 Polyclonal Antibody(C-term)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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