Product Name :
Rac-Nedisertib
Description:
Rac-Nedisertib (Rac-M3814) is a racemate of Nedisertib, a potent DNA-PK inhibitor, with an IC50 of <3 nM.DNA-PK|<3 nM (IC50) Rac-Nedisertib (Compound 137) potently inhibits DNA-PK, with an IC50 of <3 nM for DNA-PK, 0.5-5 μM for cellular pDNA-PK and 15-25 μM for KV11.1 (hERG, human ether a-go-go related gene) ).. . Thomas Fuchss, et al. Arylchinazoline. WO2014183850A1.
CAS:
1637542-34-7
Molecular Weight:
481.91
Formula:
C24H21ClFN5O3
Chemical Name:
{2-chloro-4-fluoro-5-[7-(morpholin-4-yl)quinazolin-4-yl]phenyl}(6-methoxypyridazin-3-yl)methanol
Smiles :
COC1C=CC(=NN=1)C(O)C1C=C(C(F)=CC=1Cl)C1N=CN=C2C=C(C=CC=12)N1CCOCC1
InChiKey:
MOWXJLUYGFNTAL-UHFFFAOYSA-N
InChi :
InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Escitalopram} MedChemExpress|{Escitalopram} Serotonin Transporter|{Escitalopram} Purity & Documentation|{Escitalopram} Purity|{Escitalopram} manufacturer|{Escitalopram} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Rac-Nedisertib (Rac-M3814) is a racemate of Nedisertib, a potent DNA-PK inhibitor, with an IC50 of Product information|CAS Number: 1637542-34-7|Molecular Weight: 481.{{Deruxtecan} web|{Deruxtecan} Antibody-drug Conjugate/ADC Related|{Deruxtecan} Biological Activity|{Deruxtecan} In Vitro|{Deruxtecan} manufacturer|{Deruxtecan} Epigenetic Reader Domain} 91|Formula: C24H21ClFN5O3|Chemical Name: {2-chloro-4-fluoro-5-[7-(morpholin-4-yl)quinazolin-4-yl]phenyl}(6-methoxypyridazin-3-yl)methanol|Smiles: COC1C=CC(=NN=1)C(O)C1C=C(C(F)=CC=1Cl)C1N=CN=C2C=C(C=CC=12)N1CCOCC1|InChiKey: MOWXJLUYGFNTAL-UHFFFAOYSA-N|InChi: InChI=1S/C24H21ClFN5O3/c1-33-22-5-4-20(29-30-22)24(32)16-11-17(19(26)12-18(16)25)23-15-3-2-14(10-21(15)27-13-28-23)31-6-8-34-9-7-31/h2-5,10-13,24,32H,6-9H2,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23695992 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|