Centrations were measured using the BCA method.Transient Transfections and Luciferase Activity AssayHEK293T cells in 24-well plates were transiently transfected with 1.25 mg of total DNA (expression plasmids for 900 ng…
Iptive results of continuous variables are expressed as mean and SD for Gaussian variables. Parameters that did not fulfill normal distribution were logarithmically transformed to improve symmetry for subsequent analyses.…
Contributes to muscle defects ; however, better models are needed to recapitulate disease characteristics and gain more meaningful insight into disease pathogenesis. Zebrafish are becoming an increasingly popular model for…
Arson, figure 4 A) and GCIP thickness (p = 0.0141, r = 0.35, Pearson, figure 4 B). The mean macular thickness of Wilson's disease patients correlated positively with the thickness…
Igher than the hepatic blood flow. Previous studies indicated that tissue weightnormalized blood flow to the human choroid and liver were 1200 ml/100 gm tissue/min and 1.7 ml/100 gm/min ,…
Rated high binding to the human MM cells RPMI-8226 in vitro that was significantly blocked (P,0.0001) in the presence of the cold targeting ligand. Pilot imaging studies in the orthotopic…
Ent for both LAMP-1 and 22 (LAMPnull) displayed prominent, inherent cholesterol accumulation (Figure 6A), in agreement with an earlier study . Analysis of cholesterol content demonstrated that LAMPnull cells contained…
L to mount a more efficient UPR response and maintain extracellular matrix production, which may contribute to metastasis and cell survival. Analysis of The Cancer Genome Atlas (cancergenome.nih.gov/) glioma expression…
Se substitutions in the nuclear genome. However, to the extent that oxidative stress may be weakly mutagenic and this study simply lacked sufficient power to detect the relationship, the 10781694…
Ce on a C57Bl/6 background were bred at 50-14-6 chemical information Massachusetts General Hospital and housed in a specific pathogen-free microisolator environment. C57Bl/6 mice were obtained from the Jackson Laboratory.…